BIOLOGICS IN VITILIGO
A Beacon of hope for vitiligo patients
The landscape of vitiligo treatments has witnessed a revolutionary shift with the advent of cutting-edge biologics and small molecules. Biologics are targeted systemic therapies that offer unprecedented hope for vitiligo treatment. Dermatologists at Metaderm are professionally trained to prescribe and monitor immunotherapy in vitiligo.

Key Highlights:
- Biologics are safe and effective alternatives to oral steroids.
- Biologics can only be prescribed by a qualified dermatologist
- Biologics target and inhibit specific pathways.
- More effective treatment outcomes and reduced side effects.
- Janus Kinase (JAK) inhibitors offer new hope for vitiligo patients.
- Taken orally and used as creams.
- Promising treatment in chronic autoimmune conditions.
- Works best when combined with phototherapy.
Biologics in Vitiligo at a Glance
- Best Results: 3 to 6 months
- Treatment Duration: Tailored
- Result Longevity: Permanent in most cases
- Back to Daily Activities: Immediately
- Recovery Time: 0 days
- Blood Investigations: Required
- Performed By: Dermatologist
- Cost: ₹ (Consultation required)
Our results speak for themselves






Small molecules are medicines typically taken as pills and absorbed into the body via the gut and interact with specific biologic pathways causing the disease.
Frequently Asked Questions
Biologics are special medicines made from living things like cells or proteins. They are different from regular medicines, which are made from chemicals. Biologics work by targeting specific problems in your body. They are like special keys that unlock and fix specific issues. They are more complex, more effective, and safer than regular medicines. If your doctor prescribes a biologic, it means they think it's the best option to make you feel better, but it’s essential to follow your doctor’s instructions and monitor side effects.
Biologics can effectively slow down or stop vitiligo from spreading. Some even restore skin colour in affected areas. Biologics may require ongoing treatment and monitoring to maintain their effectiveness. However, it is important to understand that vitiligo is a chronic condition. Biologics only manage the condition. It's essential to note that each patient’s response to these biologics may vary, and what works best for one person may not work for another.
The most effective biologic for vitiligo treatment is under ongoing research. However, some promising options include:
- Ruxolitinib – a topical cream that has shown significant repigmentation in clinical trials, with some patients achieving total repigmentation.
- Tofacitinib – an oral medicine that has demonstrated efficacy in vitiligo, particularly when combined with phototherapy.
You will see signs of repigmentation like darkening of skin patches, the appearance of new pigment, and your skin tone will get more even with less contrast between the affected and unaffected areas. You will start to see changes and improvements within 3 to 6 months of starting treatment. Peak response or full effect may take 6 to 12 months to become apparent. Once the biologic is working, your doctor may adjust the treatment plan to maintain the response.
Biologics, like any other medicine, can have side effects, but not everyone gets them. Consulting a dermatologist is crucial to determine the most effective treatment plan, and regular monitoring for side effects and treatment adjustment is required.